Nattokinase Powder

Product Overview

A high-potency fibrinolytic enzyme derived from the traditional Japanese food, natto. Our Nattokinase powder is produced via a controlled fermentation of non-GMO soybeans with Bacillus subtilis natto and is meticulously purified to deliver a standardized activity of 20,000 Fibrinolytic Units (FU) per gram. It is specifically engineered for formulators in the dietary supplement and functional food industries seeking a reliable, high-purity ingredient with superior performance in manufacturing.

• High-Potency & Efficacy: The standardized 20,000 FU/g activity allows for an effective, clinically relevant dose to be delivered in a smaller, consumer-friendly capsule size, enhancing user experience and compliance.
• Verified Low Vitamin K2: Each batch is tested via HPLC to ensure Vitamin K2 content is minimal (≤ 10 mcg/g). This is a critical safety and quality parameter for formulas intended to support cardiovascular wellness.
• Superior Manufacturing Properties: Optimized particle size and bulk density provide excellent flowability and uniform blending, ensuring consistent fill weights and efficient high-speed encapsulation processes.
• Traceable & Stable Supply: As a primary manufacturer, we offer a fully traceable product from fermentation to finished powder. This direct-from-factory relationship guarantees batch-to-batch consistency and a reliable, long-term supply chain for your brand.

Key Technical Parameters

Note: Bulk quantities are available from our factory with customizable packaging options upon request.

Testing and Quality Assurance

Our commitment to quality is absolute. As a leading exporter of specialty ingredients, our Nattokinase is produced in a GMP and ISO 22000 certified facility. Every batch undergoes rigorous in-house and third-party testing to verify its activity, purity, and safety, ensuring it meets and exceeds global industry standards.

Documentation Available:

• Certificate of Analysis (COA)
• Material Safety Data Sheet (MSDS)
• Allergen Statement
• Non-GMO & Non-Irradiation Statement
• Nutritional Information

Applications and Formulation Guidance

• Primary Application: Dietary Supplements (Capsules, Tablets).
• Dosage Form Recommendation: Due to the pH sensitivity of the enzyme, enteric-coated capsules are the ideal delivery system. This protects Nattokinase from degradation by stomach acid and ensures its delivery to the small intestine for optimal absorption and bioavailability.
• Formulation Note: A typical daily dose in clinical studies is 2,000 FU. Using our 20,000 FU/g powder, this can be achieved with a 100 mg dosage. Avoid exposing the powder to high temperatures (>50°C), high shear, or extreme pH conditions during blending and manufacturing.

Compatibility and Co-formulation

Our Nattokinase powder exhibits excellent compatibility with most common dry excipients, including microcrystalline cellulose (MCC), silicon dioxide, and magnesium stearate. It can be effectively co-formulated with other ingredients targeting cardiovascular health, such as Coenzyme Q10, Red Yeast Rice, and certain minerals.

Stability and Storage

• Shelf Life: 24 months from the date of manufacture.
• Storage Conditions: Store in a cool, dry place (below 20°C, <60% RH), away from direct sunlight, in its original sealed container to prevent moisture absorption and degradation of enzymatic activity.
• Stability Profile: The enzyme is most stable in a neutral pH range of 6.0-8.0.

Safety and Compliance

• Regulatory Status: Generally Recognized as Safe (GRAS) for its intended use in food and dietary supplements in the United States.
• Allergen Information: Contains Soy.
• Certifications: Non-GMO, Non-Irradiated, BSE/TSE Free. Kosher and Halal certified grades are available upon request.

Frequently Asked Questions (FAQ)

Q: How do you guarantee the 20,000 FU/g activity?

A: We use the standardized JHNFA (Japan Health and Nutrition Food Association) assay method, which is the industry gold standard for Nattokinase. This method is applied to every single batch, and the result is reported on the Certificate of Analysis (COA) provided with each shipment.

Q: Why is low Vitamin K2 important?

A: Vitamin K’s primary function is to promote blood clotting. For an ingredient intended to support healthy circulation and blood flow, the presence of Vitamin K2 could be counteractive. Our purification process specifically removes Vitamin K2, making it a safer and more effective ingredient for its target application.

Q: Do you supply directly from the factory?

A: Yes, we are the original manufacturer and a global exporter of this Nattokinase powder. Sourcing directly from us ensures you receive a product with full traceability, stable quality, a reliable supply chain, and the best possible value.

Q: What is your Minimum Order Quantity (MOQ)?

A: Our standard MOQ for this product is 25kg, typically packaged in a fiber drum. However, we understand the need for R&D and pilot batches, so please contact our sales team to discuss your project’s specific requirements.

Request a Sample or Quote

Ready to evaluate our high-performance Nattokinase powder for your next project? Contact our technical sales team to receive a no-obligation sample, a competitive quote for bulk volume, or to discuss your specific formulation needs.