Fisetin 98% Powder

Product Overview

Fisetin (CAS 528-48-3) is a distinguished flavonoid and a potent bioactive compound naturally present in the Smoke Tree (Cotinus coggygria). Our product is a high-purity, crystalline powder standardized to an exceptional concentration of 98% Fisetin. This premium grade is specifically developed for formulators in the advanced nutraceutical and functional food industries who demand maximum potency, analytical transparency, and superior performance in their products.

Characterized by its vibrant yellow hue, our Fisetin powder is engineered for optimal physical properties, making it an ingredient of choice for sophisticated dietary supplements targeting the healthy-aging and cellular wellness markets.

• High Potency & Purity: Standardized to contain a minimum of 98% Fisetin, verified by rigorous High-Performance Liquid Chromatography (HPLC) testing for unmatched accuracy and purity assurance.
• Superior Formulation Properties: An optimized particle size profile ensures excellent flowability, blend uniformity, and suitability for high-speed manufacturing processes like encapsulation and tableting.
• Transparent & Traceable Sourcing: Extracted from sustainably managed and carefully selected stems of the Cotinus coggygria tree, ensuring a pure and reliable raw material source.
• GMP-Certified Manufacturing: Produced in an ISO and GMP certified facility under stringent quality control protocols, guaranteeing product safety, consistency, and compliance.
• Direct-from-Manufacturer Supply: Sourcing directly from the original manufacturer ensures complete batch-to-batch consistency and a stable, dependable supply chain for your production needs.

Key Technical Parameters

Our Fisetin 98% powder is manufactured to meet precise specifications, providing formulators with the reliable data needed for seamless product development.

Testing & Quality Assurance

Quality is not just a metric; it’s the foundation of our manufacturing philosophy. We provide our clients with fully transparent and verifiable quality assurance.

• Methodology: We exclusively utilize High-Performance Liquid Chromatography (HPLC) for the assay of Fisetin. This highly specific method accurately separates and quantifies Fisetin, distinguishing it from other flavonoids and impurities, a level of precision that less specific methods like UV-Vis cannot provide.
• Batch-to-Batch Consistency: As the original manufacturer and exporter, we control every stage of production—from raw material sourcing to final extraction and purification. This vertical integration, combined with stringent in-process controls, ensures that every batch of Fisetin you receive delivers the same purity and physical characteristics.
• Available Documentation: To support your quality and regulatory teams, we provide a comprehensive documentation package:
  • Certificate of Analysis (COA) for each specific batch [Download a Sample COA Here]
  • Material Safety Data Sheet (MSDS)
  • Comprehensive Allergen Statement
  • Non-GMO Project Verified Statement
  • Kosher and Halal Certificates
  • Copies of our ISO 9001 and GMP manufacturing site certifications

Applications & Formulation Guidance

Our Fisetin 98% HPLC powder is engineered for performance in a range of solid and liquid dosage forms.

• Primary Applications: Its high purity and potency make it an ideal active ingredient for premium dietary supplements and functional foods focused on cellular health and longevity.
• Recommended Dosage Forms:
  • Capsules & Tablets: With excellent flowability and a controlled particle size, this grade is perfectly suited for both direct compression tableting and high-speed encapsulation, minimizing the need for additional excipients. A typical use level is between 100 mg and 250 mg per serving.
  • Powder Blends: The uniform, fine powder ensures homogenous distribution when mixed with other ingredients in sachets, stick packs, or bulk powder formulations.
  • Functional Beverages & Liquids: Formulators should note that Fisetin has low native solubility in water. For liquid applications, creating a stable suspension or utilizing solubilization technologies (e.g., lipid-based carriers, microemulsions) is recommended for optimal delivery and stability.
• Formulation Tips:
  • The inherent yellow color of Fisetin will contribute to the final product’s appearance and should be accounted for in formulation design.
  • For products focused on enhanced bioavailability, co-formulation with phospholipids or lipid-based carriers like MCT oil can be explored.

Compatibility & Co-Formulation

Fisetin is chemically stable and demonstrates excellent compatibility with a wide array of common nutraceutical ingredients. It can be effectively co-formulated with:

• Other flavonoids like Quercetin and Luteolin
• Vitamins (e.g., Vitamin C, Vitamin D3)
• Minerals (e.g., Zinc, Magnesium)
• Prebiotic fibers and other botanical extracts

It remains stable in most dry-blend systems and does not typically interact with common excipients.

Stability & Storage

Proper handling and storage are crucial to maintain the potency and shelf life of high-purity Fisetin.

• Stability: The powder is highly stable when protected from moisture. It is sensitive to degradation from prolonged exposure to strong light and high temperatures (>40°C). It is most stable in neutral to acidic pH environments and may degrade in strongly alkaline conditions.
• Storage Recommendations: To ensure maximum stability, store in tightly sealed, opaque containers in a cool (below 25°C) and dry place. Keep away from direct sunlight and sources of heat.
• Shelf Life: 24 months from the date of manufacture when stored under the recommended conditions.

Safety & Regulatory Information

• Regulatory Status: Fisetin is widely used as an ingredient in dietary supplements in the United States and other regions. It is the responsibility of the brand owner to ensure their final product complies with all local and regional regulations.
• Labeling: For US dietary supplements, the ingredient should be declared on the label as “Fisetin” or “Smoke Tree Extract (Cotinus coggygria) (stem)”.
• Safety: When used at typical dietary supplement levels, Fisetin is generally considered safe. This product is a concentrated extract intended for manufacturing and is not for direct consumption. It is not recommended for pregnant or nursing women without consulting a healthcare professional.

Frequently Asked Questions (FAQ)

Q1: Do you supply Fisetin directly from your factory?

A: Yes, we are the original manufacturer and a global supplier of Cotinus coggygria extract. This direct-from-factory model ensures full traceability, competitive pricing, and a stable, uninterrupted supply chain for our partners.

Q2: What is the extraction solvent used in the process?

A: We utilize only food-grade ethanol and purified water for the extraction process. Our purification methods are designed to effectively remove these solvents, and our final product consistently meets the strict residual solvent limits outlined in USP <467> and EP 5.4. A detailed solvent report is included in every batch-specific COA.

Q3: Can I get a sample for R&D testing and evaluation?

A: Absolutely. We encourage our clients to perform their own evaluations. Please use the contact form below to request a complimentary R&D sample. Our technical team is also available to answer any questions you may have.

Q4: What is your Minimum Order Quantity (MOQ) for this product?

A: Our standard packaging and MOQ is 25 kg in a fiber drum. However, we are flexible and can often support smaller trial orders for new product development. Please contact us with your specific quantity requirements for a customized quote.